Endocrine Abstracts

Background: Celiac disease is frequently associated with type 1 diabetes mellitus, but is usually ill-defined and not usually suspected until the disease become advance.Aim: To study the prevalence, clinical profile and glycemic variability and the effect of gluten free diet on growth and diabetic control in celiac type 1 diabetes patients in a tertiary care referral centre in north India.Materials and method: Total of 256 patients...

Background: Diabetic ketoacidosis is characterized by biochemical tired of hyperglycemia, acidosis, and ketonemia. It remains a life threatening condition despite improvement in diabetic care, timely identification and intervention remains the backbone of treatment.Aim and objectives: i) To evaluate the clinical and biochemical prognostic markers in diabetic ketoacidosis. ii) To correlate the various prognostic markers with mortality in diabetic ketoacid...

Background: Sepsis is the leading cause of mortality in the critically ill. Recent studies emphasize early classification and treatment is paramount to improving mortality rates. Recently it has been found in many studies that many trace elements and nutrients do have effect on human body and if supplemented can improve the prognosis in patients with sepsis.Aim and objectives: primary objective: Whether low vitamin D is associated with mortality.<p c...

Background: Juvenile hypothyroidism is very common problem in developing part of world, and produces various skeletal manifestations and one of them is short stature and it is the most common reason for referral to endocrinologist. It has very wide etiology and one of them is hypothyroidism, which needs special attention, as the treatment impact of thyroxin replacement has favourable outcome.Aim and objectives: To study the prevalence of juvenile hypothy...

Background: We planned this prospective cohort study in term newborn babies, with the objective to determine the incidence of vitamin D deficiency in infancy and to determine the level of vitamin D which triggers the physiological PTH axis of the body so as to differentiate truly deficient from sufficient vitamin D status.Methods: 96 participants at birth were enrolled and followed up till 9 months of age. Serum 25OHD was estimated in cord blood at birth...

Background: Juvenile hypothyroidism is very common problem in developing parts of world, and produces various skeletal manifestations. One of them is short stature and it is the most common reason for referral to endocrinologist.Aim and objectives: To study the prevalence of short stature in juvenile hypothyroidism, to study the various radiological manifestations of juvenile hypothyroidism and to study the impact of treatment on growth velocity and vari...

Background: The hypothalamic–pituitary–adrenal axis has a pivotal role in combating acute insults. Glucocorticoids play a role directly or indirectly in the maintenance of normal vascular tone and in potentiating the vasoconstrictor action of catecholamine, associated with septic shock.Aims: To determine the incidence of adrenal insufficiency (AI) and its relation to mortality in patients with septic shock.Settings and de...

Introduction: Diabetes is associated with dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels. Diabetic macrovascular complications are the leading cause of deaths in diabetics. The correlation between LVH and LVDD with HbA1c is not clear in newly diagnosed T2DM Indian diabetics.Aims and objective: To study the frequency of left ventricular hypertrophy (LVH) and left ventricular diastolic dysfuncti...

Background: Diabetic ketoacidosis is characterised by biochemical tired of hyperglycemia, acidosis, and ketonemia. It remains a life threatening condition despite improvement in diabetic care, timely identification and intervention remains the backbone of treatment.Aim and objectives: i) To evaluate the clinical and biochemical prognostic markers in diabetic ketoacidosis. ii) To correlate the various prognostic markers with mortality in diabetic ketoacid...

Background: The metabolic syndrome is one of the fastest growing epidemics of the modern era in both the industrialised as well as developing world. Waist circumference (WC) is an important component to diagnose metabolic syndrome. Cut off point of WC to diagnose metabolic syndrome is different in.different ethnic groups.Objective: To study and correlate the variation in prevalence of metabolic syndrome depending on the site of waist measurement and to s...